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  • 90. Decagram synthesis of GB13 Supplies Divergent Access to Galbulimima alkaloids

    90. Decagram synthesis of GB13 Supplies Divergent Access to Galbulimima alkaloids

    90. Freeman, S. M.; Landwehr, E. M.; Rojas, J. R.; Tanaka, R.; Bailey, J. B.; Gembicky, M.; Shenvi, R. A.* “Decagram-scale synthesis of GB13, a Galbulimima alkaloid precursor” 2025, ChemRxiv doi: 10.26434/chemrxiv-2025-490r9

  • 84. Structural basis of inverse agonism via inactive kappa opioid receptor:G protein complexes

    84. Structural basis of inverse agonism via inactive kappa opioid receptor:G protein complexes

    84. Motiwala, Z.; Tyson, A. S.; Styrpejko, D.; Han, G. W.; Khan, S.; Ramos-Gonzalez, N.; Woo, S.; Villers, K.; Landaker, D.; Shenvi, R. A.; Majumdar, S.; Gati, C. “Structural basis of inverse agonism via inactive kappa opioid receptor:G protein complexes” Nature Chem. Bio. 2025, 21, 1046–1057.

  • 82. The original caretakers of salvinorin A

    82. The original caretakers of salvinorin A

    82. Clay, K.; Shenvi, R. A. “The original caretakers of salvinorin A” Nature Chem.2024, 16, 1735–1736.

  • 75. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space

    75. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space

    75. Kotesova, S.; Shenvi, R. A. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space. Acc. Chem. Res. 2023, 56, 3089.

  • 72. A route to potent, selective and biased salvinorin chemical space

    72. A route to potent, selective and biased salvinorin chemical space

    72. Hill, S. J.§; Dao, N.§; Dang, V.; Stahl, E.; Bohn, L. Shenvi, R. A. A route to potent, selective and biased salvinorin chemical space. ACS Cent. Sci., 2023, online. §co-first authors

  • 69. Synthesis of psychotropic alkaloids from Galbulimima

    69. Synthesis of psychotropic alkaloids from Galbulimima

    69. Woo, S.; Landwehr, E.; Shenvi, R. A. Synthesis of psychotropic alkaloids from Galbulimima Tetrahedron 2022, 126, 133064. [In celebration of the 65th anniversary of Tetrahedron Publications]

  • 68. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism

    68. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism

    68. Shevick, S. L.; Freeman, S.; Tong, G.; Russo, R. J.; Bohn, L. M.; Shenvi, R. A. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism ACS Cent. Sci., 2022, 8, 948–954. DOI: https://doi.org/10.1021/acscentsci.2c00442. ChemRxiv DOI: 10.26434/chemrxiv-2021-rtxqf

  • 67. Synthesis and target annotation of GB18

    67. Synthesis and target annotation of GB18

    67. Woo, S.; Shenvi, R. A. Synthesis and target annotation of GB18. Nature, 2022, DOI: 10.1038/s41586-022-04840-9. ChemRxiv DOI: 10.26434/chemrxiv-2022-cs8v5

  • 66. Concise syntheses of GB22, GB13 and himgaline by cross-coupling and complete reduction

    66. Concise syntheses of GB22, GB13 and himgaline by cross-coupling and complete reduction

    66. Landwehr, E. M.; Baker, M. A.; Oguma, T.; Burdge, H. E.; Kawajiri, T.; Shenvi, R. A. Concise syntheses of GB22, GB13 and himgaline by cross-coupling and complete reduction. Science, 2022, 375, 1270–1274. ChemRxiv DOI: 10.26434/chemrxiv.8263415.v1

  • 58. Chemical Syntheses of the salvinorin chemotype of KOR agonist

    58. Chemical Syntheses of the salvinorin chemotype of KOR agonist

    58. Hill, S. J.; Brion, A. U. C. M.; Shenvi, R. A. Chemical Syntheses of the salvinorin chemotype of KOR agonist. Nat. Prod. Rep. 2020, 37, 1478–1496.

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