FAQ Categories Opioids

84. Clay, K.; Shenvi, R. A. “The original caretakers of salvinorin A” Nature Chem. 2024

75. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space

75. Kotesova, S.; Shenvi, R. A. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space. Acc. Chem. Res. 2023, 56, 3089.

72. A route to potent, selective and biased salvinorin chemical space

72. Hill, S. J.§; Dao, N.§; Dang, V.; Stahl, E.; Bohn, L. Shenvi, R. A. A route to potent, selective and biased salvinorin chemical space. ACS Cent. Sci., 2023, online. §co-first authors

69. Synthesis of psychotropic alkaloids from Galbulimima

69. Woo, S.; Landwehr, E.; Shenvi, R. A. Synthesis of psychotropic alkaloids from Galbulimima Tetrahedron 2022, 126, 133064. [In celebration of the 65th anniversary of Tetrahedron Publications]

68. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism

68. Shevick, S. L.; Freeman, S.; Tong, G.; Russo, R. J.; Bohn, L. M.; Shenvi, R. A. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism ACS Cent. Sci., 2022, 8, 948–954. DOI: https://doi.org/10.1021/acscentsci.2c00442. ChemRxiv DOI: 10.26434/chemrxiv-2021-rtxqf

67. Synthesis and target annotation of GB18

67. Woo, S.; Shenvi, R. A. Synthesis and target annotation of GB18. Nature, 2022, DOI: 10.1038/s41586-022-04840-9. ChemRxiv DOI: 10.26434/chemrxiv-2022-cs8v5

66. Concise syntheses of GB22, GB13 and himgaline by cross-coupling and complete reduction

66. Landwehr, E. M.; Baker, M. A.; Oguma, T.; Burdge, H. E.; Kawajiri, T.; Shenvi, R. A. Concise syntheses of GB22, GB13 and himgaline by cross-coupling and complete reduction. Science, 2022, 375, 1270–1274. ChemRxiv DOI: 10.26434/chemrxiv.8263415.v1

58. Chemical Syntheses of the salvinorin chemotype of KOR agonist

58. Hill, S. J.; Brion, A. U. C. M.; Shenvi, R. A. Chemical Syntheses of the salvinorin chemotype of KOR agonist. Nat. Prod. Rep. 2020, 37, 1478–1496.

55. Concise Synthesis of GB22 by Endo-Selective Siloxycyclopropane Arylation

55. Burdge, H. E.; Oguma, T.; Kawajiri, T.; Shenvi, R. A. Concise Synthesis of GB22 by Endo-Selective Siloxycyclopropane Arylation ChemRxiv DOI: 10.26434/chemrxiv.8263415.v1 .

47. Intermolecular Heck Coupling with Hindered Alkenes Directed by Potassium Carboxylates

47. Huffman, T.; Wu, Y.; Emmerich, A.; Shenvi, R.A. Intermolecular Heck Coupling with Hindered Alkenes Directed by Potassium Carboxylates Angew. Chem. Int. Ed. 2019, 58, 2371-2376.